An evidence-based behavioral treatment program with a 91.8% success rate, giving you a proven answer for the next parent who asks about their child's bedwetting.
Nocturnal enuresis affects approximately 15–25% of children ages 4–6, with an estimated 5–7 million children in the United States alone. Yet in most primary care settings, the condition is undertreated. Parents look to their pediatrician for guidance, yet the response they receive often falls short of what's possible.
The most common response, yet many children don't outgrow enuresis for years. At age 11, approximately 7% still wet the bed. Meanwhile, years of unnecessary distress accumulate: low self-esteem, social withdrawal, missed sleepovers, and family stress. Waiting is not a treatment strategy.
Urine tests, blood work, ultrasound, and sometimes even invasive urological procedures. These tests are costly for families and, in the vast majority of cases, return normal results. Why? Because nocturnal enuresis is typically not a medical condition. If the bladder functions normally during the day, the urinary system is not the problem.
Desmopressin addresses the symptom but not the underlying cause. It reduces urine production at night but does not train the child's reflex response. The result: extremely high relapse rates once medication is discontinued. It's a temporary measure, not a solution.
This is the key clinical insight that changes everything. Children with nocturnal enuresis typically have completely normal daytime bladder function. They don't leak, they control urination appropriately, and their urinary system operates as expected.
The same bladder that copes perfectly during waking hours fails at night. This tells us the issue is not structural or urological. Rather, the issue lies in a conditioned reflex that hasn't developed properly. The child's body does not respond to the signal of a full bladder during sleep. The arousal mechanism that should wake the child (or trigger sphincter contraction) is not functioning as it should.
Sagie, J. "The Relationship between Nocturnal Enuresis, Time of Night and Waking Response in the Process of Treatment with Enuresis Alarm." Children's Hospital Quarterly, 8(1), 1996.
This is why diagnostic tests come back normal. They're examining the anatomy and physiology of a system that is, in fact, functioning correctly. The deficit is in the conditioned reflex, and that is precisely what behavioral treatment addresses.
The Sagie treatment model has been applied in institutional clinical settings and rigorously documented. The following data comes from the Enuresis Clinic at Schneider Children's Medical Center of Israel, the country's largest pediatric hospital, affiliated with Tel Aviv University's Sackler School of Medicine.
Of 2,308 patients who completed treatment at Schneider Children's Medical Center (1994–2002), 2,119 achieved complete dryness. An additional 1.9% showed significant improvement.
Ages 4–35. 82% primary enuretics. 77% classified as idiopathic with no anatomic or psychological cause identified. 97.5% described by parents as very heavy sleepers.
A structured, time-limited intervention with a clear endpoint. Unlike "waiting it out," there is a defined timeline and measurable progress at every stage.
Across clinics worldwide since 1984. The most extensive clinical database on enuresis treatment in existence.
TheraPee is not simply an alarm. It is a comprehensive, clinically-backed behavioral treatment program. Developed by Dr. Jacob Sagie, Ph.D. and Dr. Tal Sagie, Ph.D., the program is built on the same multimodality approach that produced the documented clinical results, now delivered through an interactive online platform accessible from the patient's home.
Proprietary sensor pad that detects the first sign of moisture, activating the conditioning response cycle.
Sophisticated online system that tailors the treatment protocol to each patient's specific condition and progress.
Detailed monitoring of reflex response, wetting frequency, and urine volume, providing measurable outcomes throughout treatment.
Daily bladder capacity training, sphincter strengthening, positive reinforcement protocols, and guided exercises for child and parent.
Provide your patient's parent with a clear, professionally prepared overview of nocturnal enuresis and the TheraPee treatment program. Simply enter their email address below. They will receive the handout directly from our clinical team.
World-renowned enuresis expert and certified Family Psychotherapist specializing in the Psychophysiology of Enuresis. Treating patients since 1984, with more than 30,000 cases. Founded and directed the Enuresis Clinic at Schneider Children's Medical Center (Israel's largest pediatric hospital). Established the first enuresis clinic in China at Shanghai Children's Medical Center. His landmark research on enuresis and sleep was presented at the International Scientific Conference of the European Sleep Society.
Enuresis specialist with expertise in children's behavioral problems. Treating patients since 1999, with more than 8,000 cases worldwide. First bedwetting expert to conduct online treatment globally. Developed the TheraPee interactive platform and led R&D for the StoPee device. Published researcher and invited guest lecturer at academic institutions in Poland and Israel.